Prof. Jianping Jia, Department of Neurology, Xuan Wu Hospital,the Capital Medical University?

Director of the Department of Neurology, Xuan Wu Hospital, the Capital Medical University?
Dean of the Neurology Department of Capital Medical University?
Director of Institute of Neurology of the Capital Medical University?
Director of Center of Alzheimer's Disease, Beijing Institute for Brain Disorders?
Address: Department of Neurology, Xuan Wu Hospital of the Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, China?
Postcode: 100053?
Email: cfan_jia@163.com

Former Chairmen of the Neurology Branch of Chinese Medical Association, Former President of the Neurology Branch of Chinese Medical Doctor Association, Group Leader of Cognitive and Dementia Research Group of Chinese Medical Association Neurology Branch, Chairman of the Cognitive Disorders Professional Board of the Neurology Branch of Chinese Medical Doctor Association, Editor of Alzheimer's & Dementia, Chief Editor of Chinese version of Alzheimer's & Dementia. Chief Editor, Associate Editor, or Editor of several Chinese academic journals.

Mainly engaged in the clinical and basic research of cognitive disorders, including mild cognitive impairment (MCI) and dementia. Devoted to promote the development of clinical and research work of cognitive disorders in China. Established the largest database of MCI and AD patients in China. Founded the first registry network of FAD in China. Founded the Cognitive and Dementia Research Group of Chinese Medical Association Neurology Branch, and the Cognitive Disorders Professional Board of the Neurology Branch of Chinese Medical Doctor Association. Helps many tertiary hospitals to establish memory clinic for memory and cognitive disorders. The China Cognition and Aging Study (COAST) sponsored by Prof. Jia reported that approximately 20% of the people over the age of 65 years in China had evidence of MCI, and the prevalence of AD is similar to that of developed countries. The results of the COAST study are valuable for developing nations to makepublic health plans for elderly. Explored the pathogenic mechanisms of gene variations in promoter region of AD-associated genes, and reported 20 variations locuses in promoter region. Identified the first pathogenic mutation of PSEN1 in Chinese FAD patients, established the first transgenic AD model carrying PSEN1 mutation in China, and thoroughly explored the pathogenesis of this mutation. Worked as principal investigator and project director in several national wide multicenter clinical trials of MCI and AD, especially dedicated to investigate the efficacy and safety of Chinese traditional medicine in treatment of cognitive disorders. Presided over or participated in more than 60 national or provincial research projects, which included researching project of national "973", "863", Science-Technology Project of the National "Tenth Five-Year-Plan" of China, National 11th "Five-Year" Technology Support Programs and National Natural Science Foundation. Published 580 academic papers, more than 110 of which were published in SCI journal. Published 34 monographs. Presided over the editing of "Chinese guidelines on diagnosis and treatment of dementia and cognitive disorders". Won more than 20 national and provincial science and technology awards. The research work "The prevalence, pathogenesis, and diagnosis and treatment application research of mild cognitive impairment and dementia" leaded by Prof. Jia won the second prize of National Scientific and Technological Progress Award in 2013.

1. Jia J*, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement 2013.

2. Jia J*, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X.The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014 Jan 10. pii: S1552-5260(13)02843-4. doi: 10.1016/j.jalz.2013.09.008.

3. Xing Y, Jia J*, Ji XJ, Tian T. Estrogen associated gene polymorphisms and their interactions in the progress of Alzheimer's disease. Prog Neurobiol 2013.

4. Wang F, Shu C, Jia L, Zuo X, Zhang Y, Zhou A, Qin W, Song H, Wei C, Zhang F, Hong Z, Tang M, Wang D, Jia J*. Exploration of 16 candidate genes identifies the association of IDE with Alzheimer's disease in Han Chinese. Neurobiol Aging 2012, 33(5):1014 e1011-1019.

5. Qin W, Jia L, Zhou A, Zuo X, Cheng Z, Wang F, Shi F, Jia J*. The -980C/G polymorphism in APH-1A promoter confers risk of Alzheimer's disease. Aging Cell 2011, 10(4):711-719.

6. Cong L, Jia J*. Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer's disease. Neurobiol Aging 2011, 32(1):54-62.